For starters, a Canadian bet opens up a massive potential for profits.
Since you are essentially placing 26 different bets, if most of your selections win, you can earn a small fortune. Furthermore, unlike with simpler types of multiple bets, just two selections are enough for a win condition.
This means that you can still turn a profit, even if most of your selections lose.
However, you will need some preemptive planning and strategizing if you want to make a successful bet.